Quantitative Evaluation of the Disintegration of Orally Rapid Disintegrating Tablets by X-Ray Computed Tomography
نویسندگان
چکیده
منابع مشابه
Evaluation of disintegration properties of orally rapidly disintegrating tablets using a novel disintegration tester.
This report describes a new disintegration tester that can determine not only the disintegration time of orally rapidly disintegrating tablets (ODT), but also the disintegration behavior and mechanism. Using the tester, the disintegration properties of the tablets prepared in a previous study were examined. The purpose of this study is to confirm the utility of the tester as an instrument for e...
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Introduction: The purpose of the current study was to investigate the effect of X-ray spectra on the sensitivity of a polymer gel dosimeter imaged with a conventional computed tomography (CT) scanner. Material and Methods: The whole process of CT imaging of an irradiated polymer gel was simulated by MCNPX Monte Carlo (MC) code. The imaging of polyacrylamide gel was accomplished by means of a co...
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Pramipexole is the mostly prescribed drug in patients with Parkinson disease. The incidence of Parkinson disease is related to aging and mostly developed in elderly people with difficulty in swallowing or dysphagia. In the current study we aimed to develop an orally fast disintegrating tablet (ODT) of pramipexole as a preferable alternative in geriatric patients. Hence, the fast disintegration ...
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2012
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.c12-00556